Turmeric The Golden Dust of Ayurveda

New study shows how turmeric's curative element works


March 9, 2009 - 0 comments




Washington, March 9:Adding more to the previous studies that have poured health benefits of Turmeric, an essential spice in Indian cuisine that also has long been known for its medicinal properties, a new study has revealed that this herb with a slew of medicinal qualities can spur human cell membranes behave for better health.



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Turmeric is a yellow-coloured rhizome thought to have many medicinal properties including anti-inflammatory, antioxidant and anti-cancer define agents. In India, it is being added to every vegetable and pulses dish cooked in kitchen. Indians also use this yellow Indian spice which belongs to ginger family Zingiberaceae as a readily available antiseptic for cuts, burns and bruises.
Reference:: Sikh Philosophy Network http://www.sikhphilosophy.net/health-and-nutrition/23885-turmeric-the-golden-dust-of-ayurveda.html
Also known as the Indian Saffron, Turmeric was always considered a magical herb in India, and has been used by traditional medicine systems like Ayurveda, Unani, and Siddha for treating wounds and infections. It has also been used in cosmetic preparations.



And, now a team of science experts in the United States have discovered what makes this herbal blood purifier and antiseptic "holy powder", revealing that curcumin is the its main curative ingredient responsible for the magic healing power of Turmeric.


The scientists’ team at Michigan University, led by Indian-origin researcher Ayyalusamy Ramamoorthy, who is a Professor of Biophysics at the University of Michigan (U-M), has claimed that curcumin fights infection and promotes good health by inserting itself into cell membranes and making them more orderly. By entering blood cells, it helps improve cells' resistance to infection and malignancy.



"The membrane goes from being crazy and floppy to being more disciplined and ordered, so that information flow through it can be controlled," says Prof Ramamoorthy.
Reference:: Sikh Philosophy Network http://www.sikhphilosophy.net/showthread.php?t=23885
So far, scientists were not fully aware about how exactly curcumin works inside the body. In the latest research Prof Ramamoorthy and colleagues looked at how curcumin works to increase the body's resistance to disease.


To probe the link between curcumin and membrane, the team used a technique called solid-state nuclear magnetic resonance (NMR) spectroscopy. The researchers found that curcumin actually regulates the action of membrane proteins "indirectly", by altering the physical properties of the membrane.



"Probing high-resolution intermolecular interactions in the messy membrane environment has been a major challenge to commonly used biophysical techniques," Ramamoorthy said.



Prof. Ramamoorthy said his team is now planning to find out if other plant compounds interact with cells the same way as curcumin.


If in the other comparative studies curcumin gives desired results, then it could lead to the development of potent compounds to treat infection and other diseases, explains Ramamoorthy.



"We want to see how these various derivatives interact with the membrane, to see if the interactions are the same as observed. Such a study could lead to development of compounds to treat infection and other diseases," he said.



Prof. Ramamoorthy’s findings is published online in the Journal of the American Chemical Society.


New study shows how turmeric's curative element works | TheMedGuru

 
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Turmeric Medical Benefits, The NIH Studies and Anti Aging Vitamins

According to the Ayurvedic tradition, the turmeric medical benefits include improved healing and reduced infections. It is a readily available antiseptic for use on cuts, burns and bruises. Ayurvedic medicine is practiced primarily in India and other parts of Asia. Only recently have Western practitioners become interested in the plant.
Reference:: Sikh Philosophy Network http://www.sikhphilosophy.net/showthread.php?t=23885

Turmeric powder is used extensively in Indian cuisine. It makes a pleasant tea that is favored in some countries, including Japan. As a dietary supplement, it is used to improve digestion and help heal a variety of stomach problems. It is thought to be good for the teeth, as it has some fluoride content, although people in the US get plenty of fluoride from other sources.

Scientific research has shown that the plant is effective against some types of bacteria. Plants contain a variety of different compounds, each having different biological activity. The active compound in this particular plant is called curcumin.

So, the turmeric medical benefits are related to the curcumin content, but the content varies from plant to plant. Most supplement companies do not measure the active curcumin that is present in the extract, but the better ones do. An extract with a curcumin content of 98% is the highest that is currently available.

Supplement sales increased by 35% between 2004 and 2005, primarily due to an article published in the Wall Street Journal stating that there had been an explosion of research activity concerning curcumin. The ]National Institutes of Health currently has four different clinical trials underway to study the benefit of the compound in the treatment of cancer and Alzheimer's.

For a person that is ill, I would recommend seeking the advice of a doctor of naturopathic medicine. They are more familiar with the use of natural as well as modern treatments and how they may best be combined.

For someone that is looking for a good health supplement, you can get the turmeric medical benefits, along with your daily nutritional needs and a variety of other healthy extracts in a single supplement. There is no need to buy dozens of different supplements and take handfuls of pill every day. You could end up taking something that doesn't work well with something else, either countering its effect of causing an unwanted reaction. Good multi-nutritional supplements are carefully formulated to prevent that type of thing from occurring.

One of the turmeric medical benefits had to do with people suffering from arthritis or other inflammatory diseases. It seems to act like a COX-2 inhibitor. Prescription drugs that act as COX-2 inhibitors have been very effective pain relievers, but they are accompanied by a number of unwanted effects

Natural anti-inflammatories that inhibit COX-2 production are not accompanied by these side effects. Curcumin is only one of the known natural anti-inflammatories.

Researchers feel that these natural anti-inflammatories may reduce our risk of cancer and heart disease by countering the effects of inflammatory foods and toxins that we are exposed to on a daily basis. So, one, of the probable turmeric medical benefits, is to help prevent those life-threatening diseases and help us live longer healthier lives.
Reference:: Sikh Philosophy Network http://www.sikhphilosophy.net/showthread.php?t=23885

Valerie Rosenbaum has spent several years researching anti aging vitamin supplements and natural skincare products. As a result of that effort she has found what she believes to be the best anti aging supplement available on the market today. Learn about what she discovered at her website NaturalBalanceSupplements.com

So far 2 articles summarized for the non scientist. Here is some basic research ongoing of course.


Rapid quantitation of curcumin in turmeric via NMR and LC–tandem mass spectrometry
Food Chemistry, Volume 113, Issue 4, 15 April 2009, Pages 1239-1242
Ahmet C. Gören, Simay Çıkrıkçı, Muhiddin Çergel, Gökhan Bilsel

Turmeric (Curcuma longa)
Clinical Guide to Nutrition & Dietary Supplements in Disease Management, 2003, Pages 669-671
Jennifer R. Jamison MBBCh, PhD, EdD, FACNEM, Grad Dip Human Nutr

Postnatal modulation of hepatic biotransformation system enzymes via translactational exposure of F1 mouse pups to turmeric and curcumin
Cancer Letters, Volume 96, Issue 1, 4 September 1995, Pages 87-93
Anjali Singh, S. P. Singh, R. Bamezai

Studies on the anticlastogenic effect of turmeric and curcumin on cyclophosphamide and mitomycin C In Vivo
Food and Chemical Toxicology, Volume 36, Issue 1, January 1998, Pages 73-76
M. J. Mukhopadhyay, A. Saha, A. Mukherjee

Reversal of aflatoxin induced liver damage by turmeric and curcumin
Cancer Letters, Volume 66, Issue 2, 30 September 1992, Pages 115-121
K.B. Soni, A. Rajan, R. Kuttan

Effect of γ-irradiation on the antioxidant activity of turmeric (Curcuma longa L.) extracts
Food Research International, Volume 32, Issue 7, August 1999, Pages 487-490
Suchandra Chatterjee, S. R. Padwal Desai, Paul Thomas

Effect of Turmeric, Turmerin and Curcumin on H2O2-Induced Renal Epithelial (LLC-PK1) Cell Injury
Free Radical Biology and Medicine, Volume 24, Issue 1, 1 January 1998, Pages 49-54
Hari H. P. Cohly, Annelle Taylor, Michael F. Angel, Abdulla K. Salahudeen

Turmeric and curcumin prevents the formation of mutagenic Maillard reaction products
International Congress Series, Volume 1245, November 2002, Pages 327-334
Usha Kolpe, Vidya Ramaswamy, B. S. Satish Rao, Moolky Nagabhushan

High-performance thin layer chromatographic method for quantitative determination of curcuminoids in Curcuma longa germplasm
Food Chemistry, Volume 113, Issue 2, 15 March 2009, Pages 640-644
M. Paramasivam, R. Poi, H. Banerjee, A. Bandyopadhyay

Curcumins as inhibitors of nitrosation in vitro
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, Volume 202, Issue 1, November 1988, Pages 163-169
M. Nagabhushan, U.J. Nair, A.J. Amonkar, A.V. D'Souza, S.V. Bhide

Effect of dietary turmeric (curcuma longa) on iron-induced lipid peroxidation in the rat liver
Food and Chemical Toxicology, Volume 32, Issue 3, March 1994, Pages 279-283
A. Ch. Pulla Reddy, B. R. Lokesh

Liquid chromatography–electrospray mass spectrometric analysis of curcuminoids and sesquiterpenoids in turmeric (Curcuma longa)
Journal of Chromatography A, Volume 818, Issue 1, 28 August 1998, Pages 127-132
Xian-Guo He, Long-Ze Lin, Li-Zhi Lian, Michael Lindenmaier

Curcumin/turmeric solubilized in sodium hydroxide inhibits HNE protein modification—An in vitro study
Journal of Ethnopharmacology, Volume 110, Issue 2, 21 March 2007, Pages 368-373
Biji T. Kurien, R. Hal Scofield

Inhibition of cyclic AMP-dependent protein kinase by curcumin
Phytochemistry, Volume 42, Issue 3, June 1996, Pages 599-605
M. Hasmeda, G. M. Polya

Turmeric (Curcuma longa)-induced reduction in urinary mutagens
Food and Chemical Toxicology, Volume 29, Issue 10, 1991, Pages 699-706
K. Polasa, B. Sesikaran, T.P. Krishna, K. Krishnaswamy

A dose dependent anti-genotoxic effect of turmeric
Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Volume 446, Issue 1, 29 October 1999, Pages 135-139
R. El Hamss, M. Analla, J. Campos-Sanchez, A. Alonso-Moraga, A. Muñoz-Serrano, M. Idaomar

Behavioral, neurochemical and neuroendocrine effects of the ethanolic extract from Curcuma longa L. in the mouse forced swimming test
Journal of Ethnopharmacology, Volume 110, Issue 2, 21 March 2007, Pages 356-363
X. Xia, G. Cheng, Y. Pan, Z.H. Xia, L.D. Kong

In vitro antimutagenicity of curcumin against environmental mutagens
Food and Chemical Toxicology, Volume 25, Issue 7, July 1987, Pages 545-547
M. Nagabhushan, A.J. Amonkar, S.V. Bhide

Ferula asa-foetida and Curcuma longa in traditional medical treatment and diet in Nepal
Journal of Ethnopharmacology, Volume 67, Issue 1, October 1999, Pages 1-6
D. Eigner, D. Scholz

Antioxidant activities of curcumin, demethoxycurcumin and bisdemethoxycurcumin
Food Chemistry, Volume 98, Issue 4, 2006, Pages 720-724
G.K. Jayaprakasha, L. Jaganmohan Rao, K.K. Sakariah

Inhibition of chemical carcinogenesis by curcumin
Journal of Ethnopharmacology, Volume 27, Issues 1-2, November 1989, Pages 227-233
K.K. Soudamini, R. Kuttan

Effects of curcumin on the formation of benzo[a]pyrene derived DNA adducts in vitro
Cancer Letters, Volume 96, Issue 1, 4 September 1995, Pages 71-80
Shailesh S. Deshpande, Girish B. Maru

Turmeric: The Intriguing Yellow Spice With Medicinal Properties
EXPLORE: The Journal of Science and Healing, Volume 5, Issue 2, March 2009, Pages 114-115
Neena E. Thomas-Eapen

Curcumin, a major component of food spice turmeric (Curcuma longa) inhibits aggregation and alters eicosanoid metabolism in human blood platelets
Prostaglandins, Leukotrienes and Essential Fatty Acids, Volume 52, Issue 4, April 1995, Pages 223-227
K. C. Srivastava, A. Bordia, S. K. Verma

Multiple biological activities of curcumin: A short review
Life Sciences, Volume 78, Issue 18, 27 March 2006, Pages 2081-2087
Radha K. Maheshwari, Anoop K. Singh, Jaya Gaddipati, Rikhab C. Srimal

Action of curcumin on the cytochrome P450-system catalyzing the activation of aflatoxin B1
Chemico-Biological Interactions, Volume 100, Issue 1, 8 March 1996, Pages 41-51
P. F. Firozi, V. S. Aboobaker, R. K. Bhattacharya

Curcumin ameliorates aflatoxin-induced toxicity in mice spermatozoa
Fertility and Sterility, Volume 90, Issue 3, September 2008, Pages 775-780
Neeta Mathuria, Ramtej Jayram Verma

Protective effect of Curcumin, the active principle of turmeric (Curcuma longa) in haloperidol-induced orofacial dyskinesia and associated behavioural, biochemical and neurochemical changes in rat brain
Pharmacology Biochemistry and Behavior, Volume 88, Issue 4, February 2008, Pages 511-522
Mahendra Bishnoi, Kanwaljit Chopra, Shrinivas K. Kulkarni

Anti-depressant like effect of curcumin and its combination with piperine in unpredictable chronic stress-induced behavioral, biochemical and neurochemical changes
Pharmacology Biochemistry and Behavior, Volume 92, Issue 1, March 2009, Pages 39-43
Mohit Kumar Bhutani, Mahendra Bishnoi, Shrinivas K. Kulkarni

Antimutagenic potential of curcumin on chromosomal aberrations in Wistar rats
Mutation Research/Genetic Toxicology and Environmental Mutagenesis, Volume 515, Issues 1-2, 25 March 2002, Pages 197-202
Yogeshwer Shukla, Annu Arora, Pankaj Taneja

Can curry protect the brain from bilirubin toxicity?
Medical Hypotheses, Volume 72, Issue 6, June 2009, Pages 757-758
Benhur Sirvan Cetin, Didem Yesilirmak, Funda Tuzun, Abdullah Kumral, Nuray Duman, Hasan Ozkan

The relaxant effect of curcumin on porcine coronary arterial ring segments
Vascular Pharmacology, Volume 47, Issue 1, July 2007, Pages 25-30
Pei-Han Xu, Yuan Long, Fang Dai, Zhong-Li Liu

Effect of heat processing of spices on the concentrations of their bioactive principles: Turmeric (Curcuma longa), red pepper (Capsicum annuum) and black pepper (Piper nigrum)
Journal of Food Composition and Analysis, Volume 20, Issues 3-4, May 2007, Pages 346-351
D. Suresh, H. Manjunatha, Krishnapura Srinivasan

Differential synthesis of essential oil in callus derived microshoots of turmeric (Curcuma longa L.) in vitro
Journal of Biotechnology, Volume 136, Supplement 1, October 2008, Page S158
S. Nayak, S. Mohanty, E. Subudhi

Bubbling hookah smoke through heat-solubilized curcumin/turmeric and incorporation of the curry spice as an additive or filter in cigarettes to minimize tobacco smoke-related toxicants
Medical Hypotheses, Volume 73, Issue 3, September 2009, Pages 462-463
Biji T. Kurien, R.H. Scofield

Cardiovascular effects of ginger aqueous extract and its phenolic constituents are mediated through multiple pathways
Vascular Pharmacology, Volume 43, Issue 4, October 2005, Pages 234-241
Muhammad Nabeel Ghayur, Anwarul Hassan Gilani, Maria B. Afridi, Peter J. Houghton

Experimental studies on drying of Zingiber officinale, Curcuma longa l. and Tinospora cordifolia in solar-biomass hybrid drier
Renewable Energy, Volume 30, Issue 14, November 2005, Pages 2097-2109
Jaishree Prasad, V.K. Vijay

Distribution of photosynthetically fixed 14CO2 into curcumin and essential oil in relation to primary metabolites in developing turmeric (Curcuma longa) leaves
Plant Science, Volume 152, Issue 2, 21 March 2000, Pages 165-171
Deeksha Dixit, Neel K. Srivastava

Genetic effects of turmeric and curcumin in mice and rats
Mutation Research/Genetic Toxicology, Volume 79, Issue 2, October 1980, Pages 125-132
Vijayalaxmi

Inhibition of SOS response in E. coli PQ37 by heated turmeric and curcumin
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis, Volume 379, Issue 1, Supplement 1, September 1997, Page S206
Kalpagam Polasa, A. Nadamuni Naidu, R. Krishnaswamy

Antioxidant capacity of fresh and dried rhizomes from four clones of turmeric (Curcuma longa L.) grown in vitro
Industrial Crops and Products, Volume 25, Issue 2, February 2007, Pages 129-135


Extracts from two frequently consumed spices — Cumin (Cuminum cyminum) and turmeric (Curcuma longa) — Inhibit platelet aggregation and alter eicosanoid biosynthesis in human blood platelets
Prostaglandins, Leukotrienes and Essential Fatty Acids, Volume 37, Issue 1, July 1989, Pages 57-64
K. C. Srivastava

Chemistry and biological activities of C. longa
Trends in Food Science & Technology, Volume 16, Issue 12, December 2005, Pages 533-548
G.K. Jayaprakasha, L. Jagan Mohan Rao, K.K. Sakariah

Oral bioavailability of curcumin in rat and the herbal analysis from Curcuma longa by LC–MS/MS
Journal of Chromatography B, Volume 853, Issues 1-2, 15 June 2007, Pages 183-189
Kuo-Yi Yang, Lei-Chwen Lin, Ting-Yu Tseng, Shau-Chun Wang, Tung-Hu Tsai

Effect of curcumin on hyperglycemia-induced vascular endothelial growth factor expression in streptozotocin-induced diabetic rat retina
Biochemical and Biophysical Research Communications, Volume 361, Issue 2, 21 September 2007, Pages 528-532
T. Mrudula, P. Suryanarayana, P.N.B.S. Srinivas, G. Bhanuprakash Reddy

An unsymmetrical diarylheptanoid from Curcuma longa
Phytochemistry, Volume 19, Issue 9, 1980, Pages 2031-2032
Vijayalakshmi Ravindranath, M. N. Satyanarayana

Evaluation of turmeric (Curcuma longa) for gastric and duodenal antiulcer activity in rats
Journal of Ethnopharmacology, Volume 29, Issue 1, April 1990, Pages 25-34
S. Rafatullah, M. Tariq, M.A. Al-Yahya, J.S. Mossa, A.M. Ageel

Radioprotective action of curcumin extracted from Curcuma longa LINN: inhibitory effect on formation of urinary 8-hydroxy-2′-deoxyguanosine, tumorigenesis, but not mortality, induced by γ-ray irradiation
International Journal of Radiation Oncology*Biology*Physics, Volume 53, Issue 3, 1 July 2002, Pages 735-743
Hiroshi Inano, Makoto Onoda


Journal of Chromatography A, Volume 1111, Issue 2, 14 April 2006, Pages 281-286
Reference:: Sikh Philosophy Network http://www.sikhphilosophy.net/showthread.php?t=23885
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Reference:: Sikh Philosophy Network http://www.sikhphilosophy.net/showthread.php?t=23885
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Kumuda C. Das, Chandan K. Das

Abstract

Curcumin (diferuloylmethane) is a major component of food flavoring turmeric (Curcuma longa), and has been reported to be anticarcinogenic and anti-inflammatory. Although curcumin was shown to have antioxidant properties, its exact antioxidant nature has not been fully investigated. In this report we have investigated the possible antioxidant properties of curcumin using EPR spectroscopic techniques. Curcumin was found to inhibit the 1O2-dependent 2,2,6,6-tetramethylpiperidine N-oxyl (TEMPO) formation in a dose-dependent manner. 1O2 was produced in a photosensitizing system using rose bengal as sensitizer, and was detected as TEMP-1O2 adducts by electron paramagnetic resonance (EPR) spectroscopic techniques using TEMP as a spin-trap. Curcumin at 2.75 μM caused 50% inhibition of TEMP-1O2 adduct formation. However, curcumin only marginally inhibited (24% maximum at 80 μM) reduction of ferricytochrome c in a xanthine–xanthine oxidase system demonstrating that it is not an effective superoxide radical scavenger. Additionally, there was minor inhibition of DMPO–OH adduct formation by curcumin (solubilized in ethanol) when an ethanol control was included in the EPR spin-trapping study, suggesting that curcumin may not be an effective hydroxyl radical scavenger. Together these data demonstrate that curcumin is able only to effectively quench singlet oxygen at very low concentration in aqueous systems.
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Yeah i have heard many things about turmeric its Indian treatment and they use for cooking too,,,

No spamming links. Thank you, Narayanjot Kaur
Reference:: Sikh Philosophy Network http://www.sikhphilosophy.net/showthread.php?t=23885